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Table 3 Incidence rate ratio for common disease between non-TCM and TCM user in different age groups

From: Utilization and prescription patterns of traditional Chinese medicine for patients with hepatitis C in Taiwan: a population-based study

Age groups (year-old)

Non-TCM user

TCM user

IRR (95 % CI)

Adjusted HRb

Disease (ICD-9-CM)

N (%)

Person-years

IRa

N (%)

Person-years

IRa

(95 % CI)

Hepatitis B (70.2, 070.3, V02.61)

 All

570(19.82)

13085

43.56

1356(23.83)

39350

34.46

0.79(0.72−0.87)***

0.55(0.46−0.66)***

 18−39

88(24.18)

1901

46.3

239(25.29)

7189

33.24

0.72(0.56−0.92)**

0.41(0.25−0.69)***

 40−64

327(22.54)

6923

47.23

842(24.80)

23900

35.23

0.75(0.66−0.85)***

0.48(0.37−0.6)***

  ≥ 65

155(14.61)

4261

36.37

275(20.36)

8260

33.29

0.92(0.75−1.11)

0.82(0.58−1.17)

Liver cirrhosis (571.2, 571.5, 571.6, 572.2, 572.3, 572.4, 572.8, 573.0)

 All

989(34.39)

13085

75.58

1618(28.43)

39350

41.12

0.54(0.50−0.59)***

0.42(0.37−0.48)***

 18−39

45(12.36)

1901

23.68

108(11.43)

7189

15.02

0.63(0.45−0.90)*

0.43(0.25−0.73)**

 40−64

489(33.70)

6923

70.63

951(28.01)

23900

39.79

0.56(0.51−0.63)***

0.39(0.33−0.46)***

  ≥ 65

455(42.88)

4261

106.77

559(41.38)

8260

67.67

0.63(0.56−0.72)***

0.54(0.44−0.66)***

hepatocellular carcinoma (155)

 All

535(18.60)

13085

40.89

898(15.78)

39350

22.82

0.56(0.50−0.62)***

0.78(0.45−1.36)

 18−39

6(1.65)

1901

3.16

33(3.49)

7189

4.59

1.45(0.61−3.47)

1.25(0.12−12.75)

 40−64

242(16.68)

6923

34.96

514(15.14)

23900

21.51

0.62(0.53−0.72)***

0.98(0.43−2.21)

  ≥ 65

287(27.05)

4261

67.35

351(25.98)

8260

42.49

0.63(0.54−0.74)***

0.72(0.29−1.75)

Alcohol-related disease (291, 303.0, 303.9, 305.0, 571.0, 571.1, 571.3)

 All

294(10.22)

13085

22.47

477(8.38)

39350

12.12

0.54(0.47−0.62)***

0.41(0.32−0.51)***

 18−39

65(17.86)

1901

34.2

124(13.12)

7189

17.25

0.50(0.37−0.68)***

0.37(0.24−0.58)***

 40−64

185(12.75)

6923

26.72

290(8.54)

23900

12.13

0.45(0.38−0.55)***

0.31(0.23−0.42)***

  ≥ 65

44(4.15)

4261

10.33

63(4.66)

8260

7.63

0.74(0.50−1.09)

0.61(0.33−1.16)

Chronic obstructive pulmonary disease (491, 492)

 All

508(17.66)

13085

38.82

1402(24.64)

39350

35.63

0.92(0.83−1.12)

0.59(0.50−0.70)***

 18−39

27(7.42)

1901

14.21

120(12.70)

7189

16.69

1.18(0.77−1.78)

0.94(0.45−1.97)

 40−64

198(13.65)

6923

28.6

786(23.15)

23900

32.89

1.15(0.98−1.34)

0.67(0.52−0.86)**

  ≥ 65

283(26.67)

4261

66.41

496(36.71)

8260

60.05

0.90(0.78−1.05)

0.69(0.53−0.89)**

Diabetes Mellitus (250)

 All

1046(36.37)

13085

79.94

2143(37.66)

39350

54.46

0.68(0.63−0.73)***

0.48(0.42−0.55)***

 18−39

55(15.11)

1901

28.94

151(15.98)

7189

21

0.73(0.53−0.99)*

0.40(0.22−0.71)**

 40−64

572(39.42)

6923

82.62

1358(40.00)

23900

56.82

0.69(0.62−0.76)***

0.46(0.38−0.54)***

  ≥ 65

419(39.49)

4261

98.32

634(46.93)

8260

76.75

0.78(0.69−0.88)***

0.64(0.51−0.8)***

Thyroid disease (240, 241, 242, 244)

 All

145(5.04)

13085

11.08

631(11.09)

39350

16.04

1.44(1.21−1.73)***

0.90(0.67−1.21)

 18−39

21(5.77)

1901

11.05

105(11.11)

7189

14.6

1.32(0.83−2.11)

1.33(0.54−3.28)

 40−64

79(5.44)

6923

11.41

418(12.31)

23900

17.49

1.53(1.21−1.95)***

0.9(0.6−1.36)

  ≥ 65

45(4.24)

4261

10.56

108(7.99)

8260

13.07

1.24(0.87−1.75)

0.92(0.53−1.58)

Rheumatoid arthritis (714)

 All

89(3.09)

13085

6.8

400(7.03)

39350

10.17

1.49(1.19−1.88)***

1.18(0.82−1.69)

 18−39

11(3.02)

1901

5.79

42(4.44)

7189

5.84

1.01(0.52−1.96)

0.88(0.28−2.78)

 40−64

45(3.10)

6923

6.5

266(7.84)

23900

11.13

1.71(1.25−2.35)***

1.38(0.81−2.36)

  ≥ 65

33(3.11)

4261

7.74

92(6.81)

8260

11.14

1.44(0.97−2.14)

1.24(0.69−2.22)

Osteoarthritis (715)

 All

953(33.14)

13085

72.83

2922(51.34)

39350

74.26

1.02(0.95−1.10)

0.75(0.66−0.86)***

 18−39

46(12.64)

1901

24.2

215(22.75)

7189

29.91

1.24(0.90−1.70)

1.2(0.64−2.27)

 40−64

427(29.43)

6923

61.68

1777(52.34)

23900

74.35

1.21(1.08−1.34)***

0.85(0.71−1.03)

  ≥ 65

480(45.24)

4261

112.64

930(68.84)

8260

112.59

1.00(0.90−1.12)

0.82(0.67−1)

Depression (296.2, 296.3, 296.5, 296.6, 305.8, 311, v790, 290.13)

 All

174(6.05)

13085

13.3

650(11.42)

39350

16.52

1.24(1.05−1.47)*

0.78(0.61−1.01)

 18−39

31(8.52)

1901

16.31

128(13.54)

7189

17.8

1.09(0.74−1.62)

0.76(0.42−1.38)

 40−64

86(5.93)

6923

12.42

382(11.25)

23900

15.98

1.29(1.02−1.63)*

0.73(0.52−1.04)

  ≥ 65

57(5.37)

4261

13.38

140(10.36)

8260

16.95

1.27(0.93−1.72)

0.89(0.54−1.48)

Sicca syndrome (370.33, 710.2)

 All

78(2.71)

13085

5.96

423(7.43)

39350

10.75

1.80(1.42−2.30)***

1.27(0.86−1.89)

 18−39

4(1.10)

1901

2.1

42(4.44)

7189

5.84

2.78(1.00−7.74)

-

 40−64

40(2.76)

6923

5.78

266(7.84)

23900

11.13

1.93(1.38−2.69)***

1.14(0.67−1.94)

  ≥ 65

34(3.20)

4261

7.98

115(8.51)

8260

13.92

1.75(1.19−2.56)**

1.71(0.93−3.15)

  1. aIR incidence rate, per 1000 person-years, IRR incidence rate ratio
  2. *:<0.05; **:<0.01; *** p < 0.001
  3. bHazard Ratio adjusted for times of outpatient and inpatient visit, Charlson comorbidity index score and type of service used - only herbal medicine, only acupuncture and combination of them