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Table 1 CNS depressant activity of methanolic extract of leaves of Stericulia villosa

From: In vivo sedative activity of methanolic extract of Stericulia villosa Roxb. leaves

Time (Minute)

Hole cross test

Open field test

Control

Diazepam

MESV

Control

Diazepam

MESV

0

18.67 ± 1.08

13.00 ± 1.41

14.67 ± 2.08

135 ± 3.50

105.33 ± 2.08

147.3333 ± 12.34

30

16.67 ± 1.78

6.00 ± 1.87

11.33 ± 2.51

65.67 ± 1.32

59.00 ± 0.76

69.33 ± 16.92

60

14.33 ± 1.08

4.33 ± 0.40

9 ± 1.00

49.33 ± 1.60

34.00 ± 2.29

43 ± 13.11

90

12.67 ± 1.08

3.67 ± 0.81

7.66 ± 0.57

46.33 ± 1.04

19.67 ± 0.76

38.33 ± 6.51

120

11 ± 0.70

1.33 ± 0.40

8.67 ± 1.53

48.33 ± 2.36

17.67 ± 1.15

34.66 ± 5.13

  1. All values are expressed as mean ± SEM (n = 5); One way Analysis of Variance (ANOVA). *P < 0.05, significant compared to control