Table 2 In vitro cytotoxicity screening with SRB assay upon various extracts of Ruta angustifolia L. Pers against selected cell lines
Cell Line | A549 | CasKi | HCT-116 | MRC5 | |
|---|---|---|---|---|---|
Extract | Incubation time | IC50 (μg/ml) | |||
Methanol | 72 | 7.02 ± 0.36 | 10.56 ± 0.09 | 14.3 ± 0.93 | >100 |
48 | 51.2 ± 1.85 | 35.00 ± 1.13 | 49.9 ± 0.36 | >100 | |
24 | 85.60 ± 0.85 | >100.0 | 14.3 ± 0.93 | >100.0 | |
Hexane | 72 | 33.1 ± 1.667 | 41.20 ± 0.23 | 49.9 ± 0.36 | >100.0 |
48 | >100.0 | >100.0 | >100.0 | >100.0 | |
24 | >100.0 | >100.0 | 36.40 ± 2.01 | >100.0 | |
Chloroform | 72 | 10.1 ± 0.35 | 9.38 ± 0.49 | 88.0 ± 2.65 | >100.0 |
48 | 22.67 ± 4.31 | 29.00 ± 0.46 | >100.0 | >100.0 | |
24 | 72.0 ± 0.5 | >100.0 | 11.8 ± 0.1 | >100.0 | |
Ethyl Acetate | 72 | 35.1 ± 1.00 | 18.10 ± 0.15 | 12.40 ± 0.85 | >100.0 |
48 | >100.0 | 46.00 ± 0.76 | 27.1 ± 0.21 | >100.0 | |
24 | >100.0 | >100.0 | 23.2 ± 0.42 | >100.0 | |
Water | 72 | 73.9 ± 8.30 | 92.2 ± 2.58 | >100.0 | >100.0 |
48 | >100 | >100.0 | >100.0 | >100.0 | |
24 | >100 | >100.0 | >100.0 | >100.0 | |
Chloroform without chlorophyll | 72 | 8.8 ± 0.32 | 13.9 ± 1.23 | 10.8 ± 0.7 | 65.7 ± 0.5 |
48 | 23.20 ± 0.90 | 22.1 ± 0.21 | 14.3 ± 0.45 | >100.0 | |
24 | 88.0 ± 0.5 | >100.0 | 21.9 ± 0.46 | >100.0 | |