Fig. 6From: Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cellsUntreated control was compared with A549 cells treated at different doses and time. The morphological changes in the cells were observed under phase-contrast microscopy at 10x and 40x magnification. a A549 cells treated with different concentrations of chalepin for 48 h and observed at 10x magnification. b A549 cells treated with different concentrations of chalepin for 48 h and observed at 40x magnification. c A549 cells treated with different concentrations of chalepin 72 h and observed at 10x magnification. d A549 cells treated with different concentrations of chalepin for 72 h and observed at 40x magnification. Cells shrinkage, formation of echinoid spikes, vacuolisation, formation of apoptotic bodies and rounding were observed clearlyBack to article page