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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells

Fig. 6

Untreated control was compared with A549 cells treated at different doses and time. The morphological changes in the cells were observed under phase-contrast microscopy at 10x and 40x magnification. a A549 cells treated with different concentrations of chalepin for 48 h and observed at 10x magnification. b A549 cells treated with different concentrations of chalepin for 48 h and observed at 40x magnification. c A549 cells treated with different concentrations of chalepin 72 h and observed at 10x magnification. d A549 cells treated with different concentrations of chalepin for 72 h and observed at 40x magnification. Cells shrinkage, formation of echinoid spikes, vacuolisation, formation of apoptotic bodies and rounding were observed clearly

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