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Fig. 14 | BMC Complementary and Alternative Medicine

Fig. 14

From: Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells

Fig. 14

Western blot analysis of whole cell protein lysate of A549 cells treated with chalepin at concentration of (36 μg/ml) at 2,4,8,12, and 24 h. a Cleavage of PARP and upregulation of p53 tumor supressor factor, induced by chalepin.b Chalepin (36 μg/ml) inhibits anti-apoptotic gene products. c Chalepin induces Bax and bak expression and cytochrome c release. d Chalepin activates cleavage of procaspase 9 and procaspase 3

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BMC Complementary Medicine and Therapies

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