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Fig. 13 | BMC Complementary and Alternative Medicine

Fig. 13

From: Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells

Fig. 13

Caspase 3 activity of A549 cells treated with various concentrations of chalepin and incubated for 48 h and 72 h. a Flow cytometric analysis of apoptotic (V1-R) and non-apoptotic populations (V1-L) for active caspase 3 activity for untreated A549 cells and A549 cells treated with chalepin at various concentrations for 48 h. b Flow cytometric analysis of apoptotic (V1-R) and non-apoptotic populations (V1-L) for active caspase 3 activity for untreated A549 cells and A549 cells treated with chalepin at various concentrations for 72 h. c Bar chart representing the fold increase of caspase 3 activity in A549 cells treated with chalepin at various concentrations as compared to untreated control cells. d Bar chart representing a comparison of fold increase between chalepin treated A549 cells at different incubation times (48 & 72 h). The data expressed as mean ± S.D. of three replicates. Asterisks indicates significantly different value from control (*p < 0.05)

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