Fig. 4

a–f Docking of isolated 3-O-methyl quercetin and kaempferol with ERK1, JNK1 and p38α. Interactions of 3-O-methyl quercetin with ERK1 (a), JNK1 (b) and p38α (c); kaempferol with ERK1 (d), JNK1 (e) and p38α (f). The side chains of amino acid residues shown as sticks and subsites indicated. Pictures for representation were generated from GOLD DOCK studies. g Effect of 3-O-methyl quercetin and kaempferol on expression of phospho-p38. Cells pre-treated with isolated 3-O-methyl quercetin and kaempferol at concentration 100 μg followed by 100 μM H₂O₂ and Phospho-p38 levels determined and results were plotted (g)