TY - JOUR AU - Masoko, Peter AU - Mabusa, Itumeleng H. AU - Howard, Rachmond L. PY - 2016 DA - 2016/09/17 TI - Isolation of alpha-linolenic acid from Sutherlandia frutescens and its inhibition of Mycobacterium tuberculosis’ shikimate kinase enzyme JO - BMC Complementary and Alternative Medicine SP - 366 VL - 16 IS - 1 AB - Sutherlandia frutescens (L) R.Br. is one of traditional herbal medicines that formed the basis of primary health care systems since the earliest days and is still widely used. Sutherlandia is prescribed for people with tuberculosis (TB), but is still not known which compound(s) acts against M. tuberculosis and its mode of action. The aim of this study was to identify and isolate antimycobacterial compounds from S. frutescens extracts against shikimate kinase, a drug target for M. tuberculosis. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-016-1344-1 DO - 10.1186/s12906-016-1344-1 ID - Masoko2016 ER -