Fig. 4From: RETRACTED ARTICLE: A candidate Chinese medicine preparation-Fructus Viticis Total Flavonoids inhibits stem-like characteristics of lung cancer stem-like cellsFVTF inhibits self-renewal of LCSLCs. a, FVTF selectively inhibited the proliferation of LCSLCs in a concentration-dependent manner. b and c, FVTF significantly decrease the primary and secondary tumor sphere forming rates of LCSLCs. d, FVTF decreased expression level of the self-renewal related transcription factors Bmi1, Nanog and Oct4 in a concentration-dependent manner at 48Â h. e, FVTF decreased the expression of stem cell markers CD 133 of LCSLCs in a concentration-dependent manner as analyzed by Flow cytometry analysis at 48Â h. ISC: Isotype control, SFC: CD133+ sphere forming cells derived from NCI-H446 cells; F, FVTF decreased the expression of stem cell markers CD 44 and ALDH1 of LCSLCs in a concentration-dependent manner as analyzed by western blotting at 48Â hBack to article page