Fig. 5

EGCG alters the percentages of CD4⁺T cells, CD8⁺T cells and CD11c⁺ dendritic cells in the spleens with the improvement of IMQ-induced psoriasis-like inflammation. (a) Flow cytometric analysis of CD4⁺T cells, CD8⁺T cells and CD11c⁺ dendritic cells in the spleens. (b1, b2) The percentages of CD4⁺T cells of the two experimental groups are increased, and the percentages of CD11c⁺ dendritic cells of the two groups are obviously reduced compared to the C group. The effect of the H group is better than that of the L group (n = 6, Mean ± SEM, *P < 0.05, ** P < 0.01). (b3) No significant difference in CD8⁺T cells of spleens between the H group, L group and C group (n = 6, Mean ± SEM, P > 0.05). EGCG, Epigallocatechin-3-gallate; IMQ, imiquimod; N, the normal group; H, the high-dose group; L, the low-dose group; C, the control group.