Fig. 3

Expression of PCNA and caspase-14, infiltration of T cells were analyzed by immunohistochemistry (original magnification × 400). The numbers of positive cells were counted per high-power field (HPF) by two independent researchers. (a–d) The expression of PCNA was decreased in the early intervention group (IMQ + 6EGCG) and medium-term intervention group (IMQ +3 EGCG) compared with that in the control group. (e–h) The expression of caspase-14 was increased in the early intervention group (IMQ + 6EGCG) and medium-term intervention group (IMQ +3 EGCG) compared with that in the control group. (i- l) T cells in the dermal lesioned skin of the H and L group are significantly less than that in the C group (n = 6, Mean ± SEM, **P < 0.01). H, the high-dose group; L, the low-dose group; C, the control group