Fig. 3

Inhibitory effects of WSR on the TNF-α/IFN-γ-induced production of chemokines in HaCaT cells. The production of TARC (a), RANTES (b), MDC (c), and IL-8 (d) was measured in the culture supernatant of TNF-α/IFN-γ-stimulated HaCaT cells. Cells were pre-treated with WSR for 2 h and then stimulated with TNF-α/IFN-γ (each 10 ng/mL) for 24 h. Data are presented as the means ± SEM of three experiments. Significance *p < 0.05, **p < 0.01, ***p < 0.001