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Table 4 Quality of life of cancer patients treated with chemotherapy plus A. cinnamomea (AC) or placebo

From: A preliminary randomised controlled study of short-term Antrodia cinnamomea treatment combined with chemotherapy for patients with advanced cancer

 

Chemotherapy + AC (n = 17)

p-valuea

Chemotherapy + placebo (n = 20)

p-valuea

p-valueb

Pre-test

Post-test

 

Pre-test

Post-test

EORTCQLQ-C30

 General condition

49.51 ± 11.20

55.55 ± 28.63

0.08

53.75 ± 26.27

53.07 ± 23.10

0.28

0.76

 Fatigue

26.79 ± 27.23

34.72 ± 36.03

0.18

28.33 ± 18.19

41.52 ± 28.16

0.06

0.32

 Nausea and vomiting

22.54 ± 34.32

10 ± 18.68

0.08

9.16 ± 18.31

16.66 ± 26.64

0.24

0.51

 Pain

14.70 ± 21.95

25.55 ± 30.12

0.04

19.16 ± 23.74

21.92 ± 28.89

0.38

0.77

 Shortness of breath

9.80 ± 19.59

11.11 ± 20.57

0.31

13.33 ± 19.94

19.29 ± 25.61

0.15

0.30

 Sleep disturbance

47.05 ± 42.58

40.00 ± 36.07

0.37

46.66 ± 38.08

61.40 ± 35.59

0.01

0.04

 Lack of appetite

27.45 ± 35.81

22.22 ± 29.99

0.44

18.33 ± 27.51

31.57 ± 34.19

0.03

0.44

 Constipation

15.68 ± 20.80

17.77 ± 27.79

0.28

21.66 ± 31.11

8.77 ± 18.73

0.02

0.29

 Diarrhea

5.88 ± 13.09

6.66 ± 13.80

0.12

1.66 ± 7.45

10.52 ± 24.97

0.21

0.86

MFI - 20

 General Fatigue

10.41 ± 1.50

10.6 ± 2.26

0.35

10.55 ± 1.84

10.15 ± 2.03

0.21

0.41

 Physical Fatigue

12.23 ± 0.90

12.13 ± 1.41

0.33

11.95 ± 0.82

12.25 ± 1.11

0.24

0.78

 Reduced Activity

11.23 ± 1.60

11.66 ± 0.90

0.47

11.20 ± 1.54

11.15 ± 1.26

0.43

0.12

 Reduced Motivation

12.76 ± 1.82

13.00 ± 1.41

0.15

12.55 ± 1.23

12.50 ± 1.39

0.33

0.37

 Mental Fatigue

11.17 ± 1.07

11.33 ± 1.11

0.20

10.9 ± 1.77

11.95 ± 1.35

0.01

0.28

  1. aWilcoxon signed-rank test (Within group)
  2. bMann-Whitney U test (Differences in efficacy between two groups)