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Table 6 The effects of extracts on serum hormones and MDA levels in rats

From: Comparative evaluation of the sexual functions and NF-κB and Nrf2 pathways of some aphrodisiac herbal extracts in male rats

Item Groups --P--
Control Sildenafil Mucuna pruriens Tribulus terrestris Ashwagandha
FSH, mIU/ml 0.33 ± 0.22 0.40 ± 0.37 0.31 ± 0.25 0.34 ± 0.39 0.31 ± 0.24 >0.05
LH, mIU/ml 0.22 ± 0.29 0.30 ± 0.23 0.25 ± 0.17 0.24 ± 0.19 0.27 ± 0.19 >0.05
Testosterone, ng/ml 2.27 ± 0.17c 4.14 ± 0.71a 2.57 ± 0.44c 3.99 ± 0.16ab 3.58 ± 0.18b 0.0001
Serum MDA, μmol/L 0.54 ± 0.05a 0.56 ± 0.06a 0.49 ± 0.04b 0.38 ± 0.02c 0.44 ± 0.02b 0.0001
Testis MDA, nmol/g 1.64 ± 0.09ab 1.68 ± 0.09a 1.55 ± 0.06cb 1.45 ± 0.09d 1.51 ± 0.07cd 0.0001
  1. FSH follicle-stimulating hormone, LH luteinizing hormone, MDA malonaldeyhde; Control, no treatment; Sildenafil, rats treated with Sildenafil (5 mg/kg/d); Mucuna, rats treated with Mucuna pruriens (300 mg/kg bw); Tribulus; rats treated with Tribulus terrestris (300 mg/kg bw); Ashwagandha; rats treated with Ashwagandha (300 mg/kg bw). Data are LS means ± SE (n = 7). Different superscripts in the same row (a–c) indicate group mean differences (p < 0.05)