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Table 1 Cytotoxic activity of various samples of Rumex hastatus against HeLa and NIH/3T3 cell lines

From: Evaluation of Rumex hastatus D. Don for cytotoxic potential against HeLa and NIH/3T3 cell lines: chemical characterization of chloroform fraction and identification of bioactive compounds

Samples Conc. (μg/ml) HeLa Cell Line NIH/3T3 Cell Line
Inhibition (%) IC50 (μg/ml) Inhibition (%) IC50 (μg/ml)
Rh.Cr 500 63.25 ± 0.20*** 347.33 74.96 ± 0.21*** 174.52
250 41.43 ± 1.15*** 59.46 ± 0.54***
125 29.00 ± 1.50*** 43.07 ± 1.02***
62.5 20.64 ± 1.60*** 35.53 ± 0.61***
Rh.Hex 500 36.33 ± 3.50*** 572.61 53.86 ± 0.85*** 439.26
250 15.46 ± 2.43*** 40.60 ± 0.41***
125 07.33 ± 0.68*** 28.33 ± 0.33***
62.5 05.03 ± 0.23*** 21.50 ± 0.60***
Rh.Chf 500 81.50 ± 0.86*** 151.52 82.13 ± 0.88*** 53.37
250 69.00 ± 2.80*** 70.66 ± 0.49***
125 43.66 ± 0.89*** 64.02 ± 1.11***
62.5 34.22 ± 0.23*** 51.43 ± 0.61***
Rh.EtAc 500 79.66 ± 0.89*** 166.50 72.76 ± 0.78*** 158.73
250 66.32 ± 1.30*** 59.00 ± 0.57***
125 40.93 ± 0.49*** 46.86 ± 0.85***
62.5 29.83 ± 1.36*** 31.43 ± 0.81***
Rh.Aq 500 60.83 ± 1.36*** 369.68 65.60 ± 0.41*** 237.62
250 42.53 ± 0.46*** 51.96 ± 0.21***
125 33.61 ± 1.70*** 42.66 ± 0.49***
62.5 21.33 ± 0.33*** 36.13 ± 0.88***
Doxorubicin 500 96.63 ± 1.67 <0.1 98.53 ± 1.09 <0.1
250 91.87 ± 0.25 93.76 ± 0.78
125 89.46 ± 2.43 90.33 ± 0.88
62.5 84.50 ± 0.86 87.46 ± 0.54
  1. Data is represented as mean ± S.E.M; n = 3, ***: P < 0.001
  2. Key: Rh.Cr Crude methanolic extract, Rh.Hex n-hexane fraction, Rh.Chf chloroform fraction, Rh.EtAc ethyl acetate fraction, Rh.Aq aqueous fraction