Skip to main content

Table 2 Inhibitory activities of the nine South African medicinal plants used traditionally in the management of different inflammatory disorders on nitric oxide production and cell viability in LPS-activated RAW 264.7 macrophages

From: The anti-arthritic, anti-inflammatory, antioxidant activity and relationships with total phenolics and total flavonoids of nine South African plants used traditionally to treat arthritis

Plants Concentration (μg/mL) NO (μM) % NO inhibition % Macrophage viability
Hypericum roeperianum 100 2.46 ± 0.17 89.72 50.40
30 4.55 ± 0.25 81.04 89.40
10 8.28 ± 0.17 65.90 97.53
2 16.93 ± 1.43 29.41 100
Cremaspora triflora 100 6.15 ± 0.34 74.34 88.22
30 16.21 ± 0.25 32.39 89.71
10 18.36 ± 0.76 23.45 97.58
2 20.32 ± 1.52 15.26 100
Heteromorpha arborescens 100 0.08 ± 1.52 99.65 45.13
30 2.52 ± 0.08 89.48 82.12
10 7.52 ± 0.59 68.63 95.90
2 23.77 ± 0.17 0.87 100
Pittosporum viridiflorum 100 0.32 ± 0.17 98.66 95.66
30 4.67 ± 0.08 80.54 100
10 16.69 ± 0.25 30.40 100
2 24.43 ± 0.25 1.86 100
Bolusanthus speciosus 100 0.44 ± 0.84 98.16 34.25
30 9.25 ± 0.17 61.43 100
10 15.32 ± 0.17 36.11 98.35
2 19.55 ± 0.08 18.49 99.80
Calpurnia aurea 100 1.21 ± 0.25 94.94 60.27
30 18.60 ± 0.08 22.46 100
10 21.04 ± 0.00 12.29 96.50
2 23.30 ± 0.17 2.85 79.51
Maesa lanceolata 100 0.01 ± 0.00 100 9.29
30 0.20 ± 0.00 99.16 16.96
10 10.44 ± 0.17 56.47 22.12
2 12.58 ± 0.17 47.53 69.63
Elaeodendron croceum 100 1.21 ± 0.25 94.94 48.92
30 6.93 ± 0.25 71.11 69.65
10 14.31 ± 0.08 40.33 90.22
2 20.74 ± 0.42 13.53 >100
Morus mesozygia 100 0.20 ± 0.12 99.16 57.07
30 11.15 ± 0.12 53.49 100
10 20.68 ± 0.36 13.77 100
2 23.18 ± 0.12 3.35 95.05
Quercetin 100 0.79 ± 0.00 83.12 37.71
30 1.10 ± 0.00 100 51.89
10 1.40 ± 0.00 100 68.79
2 1.44 ± 0.00 100 66.30