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Table 2 Inhibitory activities of the nine South African medicinal plants used traditionally in the management of different inflammatory disorders on nitric oxide production and cell viability in LPS-activated RAW 264.7 macrophages

From: The anti-arthritic, anti-inflammatory, antioxidant activity and relationships with total phenolics and total flavonoids of nine South African plants used traditionally to treat arthritis

Plants

Concentration (μg/mL)

NO (μM)

% NO inhibition

% Macrophage viability

Hypericum roeperianum

100

2.46 ± 0.17

89.72

50.40

30

4.55 ± 0.25

81.04

89.40

10

8.28 ± 0.17

65.90

97.53

2

16.93 ± 1.43

29.41

100

Cremaspora triflora

100

6.15 ± 0.34

74.34

88.22

30

16.21 ± 0.25

32.39

89.71

10

18.36 ± 0.76

23.45

97.58

2

20.32 ± 1.52

15.26

100

Heteromorpha arborescens

100

0.08 ± 1.52

99.65

45.13

30

2.52 ± 0.08

89.48

82.12

10

7.52 ± 0.59

68.63

95.90

2

23.77 ± 0.17

0.87

100

Pittosporum viridiflorum

100

0.32 ± 0.17

98.66

95.66

30

4.67 ± 0.08

80.54

100

10

16.69 ± 0.25

30.40

100

2

24.43 ± 0.25

1.86

100

Bolusanthus speciosus

100

0.44 ± 0.84

98.16

34.25

30

9.25 ± 0.17

61.43

100

10

15.32 ± 0.17

36.11

98.35

2

19.55 ± 0.08

18.49

99.80

Calpurnia aurea

100

1.21 ± 0.25

94.94

60.27

30

18.60 ± 0.08

22.46

100

10

21.04 ± 0.00

12.29

96.50

2

23.30 ± 0.17

2.85

79.51

Maesa lanceolata

100

0.01 ± 0.00

100

9.29

30

0.20 ± 0.00

99.16

16.96

10

10.44 ± 0.17

56.47

22.12

2

12.58 ± 0.17

47.53

69.63

Elaeodendron croceum

100

1.21 ± 0.25

94.94

48.92

30

6.93 ± 0.25

71.11

69.65

10

14.31 ± 0.08

40.33

90.22

2

20.74 ± 0.42

13.53

>100

Morus mesozygia

100

0.20 ± 0.12

99.16

57.07

30

11.15 ± 0.12

53.49

100

10

20.68 ± 0.36

13.77

100

2

23.18 ± 0.12

3.35

95.05

Quercetin

100

0.79 ± 0.00

83.12

37.71

30

1.10 ± 0.00

100

51.89

10

1.40 ± 0.00

100

68.79

2

1.44 ± 0.00

100

66.30