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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Ethanolic extract of Schizonepeta tenuifolia attenuates osteoclast formation and activation in vitro and protects against lipopolysaccharide-induced bone loss in vivo

Fig. 5

EEST recovers LPS-induced inflammatory bone loss in mice. a Mice were sacrificed 8 days after the first LPS injection and 2D or 3D radiographs of the coronal and transverse planes of the proximal femora were obtained by micro-CT. b The BV/TV, Tb.Sp, Tb.Th, and Tb.N of the femora were determined using the micro-CT data and analyzed by INFINITT-Xelis software. ***P < 0.001 vs. control; ##P < 0.01, ###P < 0.001 vs. LPS group. c Dissected femora were fixed, decalcified, embedded, and sectioned. Sections were stained with TRAP and H&E. d The number of osteoclasts per field of tissue was counted by histomorphometric analysis

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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