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Table 1 Measurement of nitrite radicals as a measure of the levels of nitric oxide secretion in PBMCs stimulated with PG-S. aureus (100 μg/mL) and treated with various doses of uMakhonya®. Treatment of stimulated PBMCs with various doses of uMakhonya® did not effect a significant increase (p > 0.05) in NO secretion when compared to untreated, PG-S. aureus-stimulated-only and a significant increase (p > 0.05) in NO secretion when compared to PG-stimulated plus cyclosporine-treated samples

From: Evaluation of the immunomodulatory effects of a South African commercial traditional immune booster in human peripheral blood mononuclear cells

 

Untreated PBMCs

PG-S. aureus

PG-S. aureus plus Cyclosporine

PG-S. aureus plus uMakhonya® (μg/mL)

NO concentration (μM)

   

100

50

10

1

9.21

10.12

10.24

9.15

9.33

9.03

2

9.21

9.82

10

9.15

9.56

9.27

3

10.55

11.52

11.33

10.48

10.79

11.03

Mean ± SEM

9.66 ± 0.770

10.49 ± 0.905

10.53 ± 0.710

9.60 ± 0.770

9.90 ± 0.780

9.78 ± 1.092

  1. SEM standard error of the mean