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Table 1 Effect of the 80 % methanol extract of A. remota on castor oil induced diarrhea in mice

From: Antidiarrheal activity of 80 % methanol extract of the aerial part of Ajuga remota Benth (Lamiaceae) in mice

Group (mg/kg) Onset of diarrhea (min) Mean wt. of wet stools in 4 h (g) Mean no. of wet stools in 4 h Total no. of stools in 4 h PI
Control 67.00 ± 2.51 0.69 ± .04 9.00 ± 1.09 11.00 ± 1.26  
Loperamide5 174.33 ± 14.99a*** 0.22 ± .05a*** 3.00 ± .73 a*** 4.00 ± .07 a*** 66.7 %
MEAR 200 94.67 ± 1.64b**c***d** 0.53 ± .02b***c***d** 6.83 ± .60b**c***d** 10.00 ± .57b**c***d** 12.9 %
MEAR 400 151.33 ± 1.42a***f* 0.35 ± .01a*** 4.17 ± .30a***c* 6.00 ± .73a**f** 53.7 %
MEAR 600 164.67 ± 15.14a*** 0.28 ± .05a*** 3.00 ± .63 a*** 4.00 ± .85a*** 66.7 %
MEAR 800 190.00 ± 19.65 a*** 0.15 ± .05a***e* 1.83 ± .60a*** 2.00 ± .94 a*** 79.6 %
  1. Values are expressed as Mean ± SEM.(n = 6 mice) aagainst control, bagainst standard, cagainst 800 MEAR, dagainst 600 MEAR, eagainst 400 MEAR, fagainst 200 MEAR * p < 0.05, ** p < 0.01, *** p < 0.001., numbers refers to dose in mg/kg, PI refers to percent inhibition of defecation