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Table 3 Changes on body weight and organ weight after oral administration of GAE in diabetic rats

From: Antidiabetic, antihyperlipidemic and antioxidant properties of ethanol extract of Grewia asiatica Linn. bark in alloxan-induced diabetic rats

Group (n = 5)

Body weight (g)

Heart weight (g)

Liver weight (g)

Pancreas weight (g)

H/B (g/kg)

L/B g/kg)

P/B (g/kg)

 NC

150 ± 7

0.48 ± 0.025

5.51 ± 0.47

0.40 ± 0.04

3.1 ± 0.1

35.5 ± 1.23

2.3 ± 0.4

 DC

120 ± 6†

0.34 ± 0.025†

3.5 ± 0.22†

0.25 ± 0.02†

2.6 ± 0.2

26.5 ± 2.7†

2.0 ± 0.08

 DS

143 ± 7

0.49 ± 0.03

5.1 ± 0.81

0.38 ± 0.04

3.2 ± 0.22

34.2 ± 2.5

2.2 ± 0.26

GAE200

136 ± 6

0.47 ± 0.035

4.23 ± 0.26

0.30 ± 0.03

3.25 ± 0.1

30 ± 1

2.1 ± 0.1

GAE400

130 ± 5

0.45 ± 0.023

4.11 ± 0.25

0.26 ± 0.035

3.3 ± 0.23

30.5 ± 1.1

2.0 ± 0.02

  1. Data expressed as means ± SEM. H/B ratio of heart weight to body weight, L/B ratio of liver weight to body weight, P/B ratio of pancreas weight to body weight. †p <0.01 compared to NC