Fig. 2

Histological improvement in response to curcumin in TNBS-induced IBD. a After TNBS treatment at indicated time, colons were isolated and harvested. With H&E staining, the histological changes were observed. The damage including mucosal ulceration, thickened wall, and inflammatory cells infiltration occurred in the TNBS-treated group, however, the damage was reduced with curcumin pretreatment. b Histological damage score were evaluated with time course. There were 20 rats were evaluated for each score. *P < 0.05, **P < 0.01, ***P < 0.001