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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Anticonvulsant effects of iridoid glycosides fraction purified from Feretia apodanthera Del. (Rubiaceae) in experimental mice models of generalized tonic-clonic seizures

Fig. 5

Effects of iridoids glycosids extract from the stem barks Feretia apodanthera on acute 50 mg/kg pentylenetetrazole-induced seizures in mice. Panel (a) hippocampal and cortical paroxysmal discharges, panel (b) number of crisis (n/20 min), panel (c) cumulative duration of crisis (sec/20 min), panel (d) mean duration of crisis (sec). N = 6 animals per dose. Data were analysis by two-way repeated measures analysis of variance, followed by Newman-Keuls post hoc test, a P < 0.05, b P < 0.01, c P < 0.001, significantly different compared to the vehicle; Clonaz, clonazepam 0.1 mg/kg. IGEFA, iridoids glycosids extract of Feretia apodanthera

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