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Table 3 Antipyretic activity of Monotheca buxifolia hydro-ethanolic extract (MBHE) in brewer’s yeast induced pyrexia in mice

From: Pharmacological screening of Monotheca buxifolia (Falc.) A. DC. for antinociceptive, anti-inflammatory and antipyretic activities

Treatment 1st h 2nd h 3rd h 4th h 5th h
Group 1
(Brewer’s yeast + Saline)
100.4 ± 0.358 100.5 ± 0.346 100.0 ± 0.335 100.4 ± 0.265 100.5 ± 0.341
Group 2
(Acetaminophen 150 mg/kg)
96.18 ± 0.757*** 96.62 ± 0.755*** 95.50 ± 1.023*** 96.07 ± 0.720*** 95.23 ± 0.731***
Group 3
(MBHE 50 mg/kg)
97.93 ± 0.449 98.20 ± 0.634* 98.58 ± 0.838 99.27 ± 0.860 99.88 ± 0.812
Group 4
(MBHE 100 mg/kg)
96.02 ± 0.884*** 97.18 ± 0.570** 97.68 ± 0.244* 97.72 ± 0.342* 97.42 ± 0.709*
Group 5
(MBHE 150 mg/kg)
93.70 ± 0.753*** 96.93 ± 0.584*** 96.48 ± 0.303** 97.33 ± 0.547** 96.35 ± 0.837**
  1. Values are expressed as mean rectal temperature in °F ± SD. ANOVA followed by Dunnett’s post hoc test. *P < 0.05, **P < 0.01, ***P < 0.001 compared to group 1. n = 6 animals per group