Skip to main content

Table 2 Anti-inflammatory activity of Monotheca buxifolia hydro-ethanolic extract (MBHE) in carrageenan induced paw edema in mice

From: Pharmacological screening of Monotheca buxifolia (Falc.) A. DC. for antinociceptive, anti-inflammatory and antipyretic activities

Treatment 1st h 2nd h 3rd h 4th h 5th h
Group 1
Saline
0.235 ± 0.012 0.227 ± 0.026 0.240 ± 0.011 0.210 ± 0.016 0.230 ± 0.036
Group 2
Carrageenan
0.340 ± 0.016### 0.370 ± 0.028### 0.395 ± 0.025### 0.490 ± 0.057### 0.440 ± 0.028###
Group 3
Aspirin (150 mg/kg)
0.255 ± 0.028** 0.250 ± 0.035*** 0.252 ± 0.020*** 0.325 ± 0.052*** 0.305 ± 0.019***
Group 4
(MBHE 50 mg/kg)
0.262 ± 0.022** 0.282 ± 0.012** 0.287 ± 0.025*** 0.292 ± 0.015*** 0.352 ± 0.029**
Group 5
(MBHE 100 mg/kg)
0.227 ± 0.040*** 0.277 ± 0.035** 0.290 ± 0.046*** 0.287 ± 0.037*** 0.347 ± 0.029**
Group 6
(MBHE 150 mg/kg)
0.210 ± 0.028*** 0.257 ± 0.026*** 0.287 ± 0.022*** 0.272 ± 0.044*** 0.330 ± 0.038**
  1. Values are expressed as mean paw volume in ml ± SD. ANOVA followed by Tukey’s post hoc test. ###P < 0.001 compared to group 1. **P < 0.01, ***P < 0.001 compared to group 2. n = 6 animals per group