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Table 2 Anti-inflammatory activity of Monotheca buxifolia hydro-ethanolic extract (MBHE) in carrageenan induced paw edema in mice

From: Pharmacological screening of Monotheca buxifolia (Falc.) A. DC. for antinociceptive, anti-inflammatory and antipyretic activities

Treatment

1st h

2nd h

3rd h

4th h

5th h

Group 1

Saline

0.235 ± 0.012

0.227 ± 0.026

0.240 ± 0.011

0.210 ± 0.016

0.230 ± 0.036

Group 2

Carrageenan

0.340 ± 0.016###

0.370 ± 0.028###

0.395 ± 0.025###

0.490 ± 0.057###

0.440 ± 0.028###

Group 3

Aspirin (150 mg/kg)

0.255 ± 0.028**

0.250 ± 0.035***

0.252 ± 0.020***

0.325 ± 0.052***

0.305 ± 0.019***

Group 4

(MBHE 50 mg/kg)

0.262 ± 0.022**

0.282 ± 0.012**

0.287 ± 0.025***

0.292 ± 0.015***

0.352 ± 0.029**

Group 5

(MBHE 100 mg/kg)

0.227 ± 0.040***

0.277 ± 0.035**

0.290 ± 0.046***

0.287 ± 0.037***

0.347 ± 0.029**

Group 6

(MBHE 150 mg/kg)

0.210 ± 0.028***

0.257 ± 0.026***

0.287 ± 0.022***

0.272 ± 0.044***

0.330 ± 0.038**

  1. Values are expressed as mean paw volume in ml ± SD. ANOVA followed by Tukey’s post hoc test. ###P < 0.001 compared to group 1. **P < 0.01, ***P < 0.001 compared to group 2. n = 6 animals per group