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Table 4 Effect of crude hydromethanolic extract of root of Indigofera spicata on misoprostol induced GI secretion in mice

From: Antidiarrheal activity of crude methanolic root extract of Idigofera spicata Forssk.(Fabaceae)

Group Weight of small intestine (g) Intestinal fluid accumulation ratio Weight of intestinal fluid (g) % Inhibition of intestinal fluid accumulation ratio
NS 1.94 ± 0.52 0.109 ± 0.008 0.4567 ± 0.11 0.00
3 mg/kg Lop 1.38 ± 0.81 0.084 ± 0.004* 0.1567 ± 0.01* 22.81
100 mg/kg IS 1.46 ± 0.35 0.088 ± 0.004 0.1367 ± 0.03* 19.21
200 mg/kg IS 1.45 ± 0.67 0.090 ± 0.006 0.1383 ± 0.01* 17.27
400 mg/kg IS 1.59 ± 0.41 0.096 ± 0.005 0.1650 ± 0.03* 11.81
  1. Values are mean ± S.E. (n = 6), * for p < 0.05 compared to the negative control