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Table 4 Effect of crude hydromethanolic extract of root of Indigofera spicata on misoprostol induced GI secretion in mice

From: Antidiarrheal activity of crude methanolic root extract of Idigofera spicata Forssk.(Fabaceae)

Group

Weight of small intestine (g)

Intestinal fluid accumulation ratio

Weight of intestinal fluid (g)

% Inhibition of intestinal fluid accumulation ratio

NS

1.94 ± 0.52

0.109 ± 0.008

0.4567 ± 0.11

0.00

3 mg/kg Lop

1.38 ± 0.81

0.084 ± 0.004*

0.1567 ± 0.01*

22.81

100 mg/kg IS

1.46 ± 0.35

0.088 ± 0.004

0.1367 ± 0.03*

19.21

200 mg/kg IS

1.45 ± 0.67

0.090 ± 0.006

0.1383 ± 0.01*

17.27

400 mg/kg IS

1.59 ± 0.41

0.096 ± 0.005

0.1650 ± 0.03*

11.81

  1. Values are mean ± S.E. (n = 6), * for p < 0.05 compared to the negative control