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Table 2 Effect of crude hydromethanolic extract of root of Indigofera spicata on castor oil induced diarrhea in mice

From: Antidiarrheal activity of crude methanolic root extract of Idigofera spicata Forssk.(Fabaceae)

Group Onset of diarrhea (min) Total number of faeces in 4 h (frequency of defecation in 4 h) Mean evacuation index Fluid content of the faces (g) % Inhibition of diarrhea
NS 63.33 ± 5.58 11.83 ± 1.30 2.39 ± 0.09 0.78 ± 0.13 0.00
3 mg/kg Lop 99.17 ± 18.14 5.83 ± 0.75* 2.29 ± 0.15 0.36 ± 0.05* 51.02
100 mg/kg IS 71.83 ± 5.67 9.17 ± 0.70 2.34 ± 0.06 0.61 ± 0.11 22.49
200 mg/kg IS 75.33 ± 4.86 6.67 ± 1.52* 2.17 ± 0.08 0.32 ± 0.09* 43.62
400 mg/kg IS 121.17 ± 12.18*ab 5.50 ± 0.67* 1.96 ± 0.16 0.35 ± 0.08* 53.51
  1. Values are mean ± S.E. (n = 6), * for p < 0.05 compared to the negative control, a for p < 0.05compared to 100 mg/kg IS and b for p < 0.05 compared to 200 mg/kg IS