Fig. 4
Histological examination of liver sections from different groups. Liver sections from healthy control show normal hepatocytes architecture (a), whereas CCl4 treatment resulted in damaged cells, shrunken nuclei, mitotic activity (arrow heads) and centrilobular congestion (b & c). SFEE treatment resulted in restoration of the normal architecture and absence of congestion (e & f) in a similar way to that observed in silymarin treatment (d). Bars represent mean ± SEM of histopathological scoring (g) inflammation score and (h) fibrosis score. #, *: significantly different compared to CCl4-treated group or control group respectively, p < 0.05. Significance was calculated using Kruskal-Wallis test followed by Dunn’s multiple comparison post hoc test