Table 6 Hematological parameters of male rats in chronic toxicity test
From: Acute and chronic toxicities of Bacopa monnieri extract in Sprague-Dawley rats
Hematological parameter | Control | B. monnieri extract | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
30 mg/kg | 60 mg/kg | 300 mg/kg | 1,500 mg/kg | Satellite group | ||||||||||||||
RBC (x106/μl) | 9.76 | ± | 0.18 | 8.53 | ± | 0.89* | 10.03 | ± | 0.30 | 9.53 | ± | 0.30 | 9.60 | ± | 0.21 | 10.73 | ± | 0.20 |
HB (g/dl) | 16.99 | ± | 0.23 | 16.73 | ± | 0.50 | 16.92 | ± | 0.43 | 16.73 | ± | 0.51 | 16.77 | ± | 0.41 | 17.82 | ± | 0.28 |
HCT (%) | 52.00 | ± | 0.91 | 51.00 | ± | 1.86 | 52.90 | ± | 1.55 | 50.60 | ± | 1.58 | 50.50 | ± | 1.30 | 57.50 | ± | 0.98* |
MCV (fl) | 53.00 | ± | 0.21 | 53.40 | ± | 0.31 | 52.60 | ± | 0.27 | 53.00 | ± | 0.30 | 52.50 | ± | 0.27 | 53.50 | ± | 0.31 |
MCH (pg) | 17.38 | ± | 0.17 | 17.54 | ± | 0.09 | 16.85 | ± | 0.15 | 17.54 | ± | 0.11 | 16.41 | ± | 1.03 | 16.56 | ± | 0.12 |
MCHC (g/dl) | 32.80 | ± | 0.28 | 32.91 | ± | 0.26 | 32.07 | ± | 0.25 | 33.16 | ± | 0.19 | 33.18 | ± | 0.22 | 30.92 | ± | 0.12* |
PLT (x105/μl) | 0.95 | ± | 0.03 | 0.86 | ± | 0.03 | 0.97 | ± | 0.03 | 0.93 | ± | 0.04 | 1.85 | ± | 0.89 | 0.89 | ± | 0.04 |
WBC (x103/μl) | 7.70 | ± | 0.42 | 7.23 | ± | 0.69 | 9.52 | ± | 0.40 | 11.62 | ± | 1.44* | 10.01 | ± | 0.72* | 7.79 | ± | 0.60 |
NEU (x103/μl) | 1.37 | ± | 0.16 | 1.80 | ± | 0.23 | 2.12 | ± | 0.22 | 2.89 | ± | 1.19* | 2.18 | ± | 0.26 | 2.10 | ± | 0.26 |
LYMP (x103/μl) | 5.94 | ± | 0.28 | 5.14 | ± | 0.52 | 6.90 | ± | 0.29 | 8.08 | ± | 0.50* | 7.31 | ± | 0.50* | 5.31 | ± | 0.55 |
MONO (x103/μl) | 0.27 | ± | 0.06 | 0.21 | ± | 0.07 | 0.30 | ± | 0.07 | 0.49 | ± | 0.17 | 0.45 | ± | 0.12 | 0.35 | ± | 0.06 |
EOS (x103/μl) | 0.11 | ± | 0.05 | 0.08 | ± | 0.03 | 0.20 | ± | 0.08 | 0.06 | ± | 0.05 | 0.07 | ± | 0.03 | 0.02 | ± | 0.02 |
BASO (x103/μl) | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 |