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Table 2 Percentage of live, apoptotic and dead cells after 24 h after exposure to PINO (0.001, 0.01, 0.1 1 10 and 100 μM)

From: Phytoestrogen (+)-pinoresinol exerts antitumor activity in breast cancer cells with different oestrogen receptor statuses

  MDA-MB-231 MCF7 MCF10A
  Live Apoptotic Death Live Apoptotic Death Live Apoptotic Death
Control 83.22 ± 5.33 14.82 ± 4.76 1.95 ± 0.6 92,03 ± 2,69 6,97 ± 2,9 1,26 ± 0,61 98.14 ± 0.47 1.33 ± 0.42 0.5 ± 0.08
0.001 μM 82.17 ± 4.76 15.56 ± 5.56 2.25 ± 0.94 92,38 ± 1,82 6,2 ± 1,83 1,07 ± 0,62 96.17 ± 0.76 2.73 ± 0.48 1.08 ± 0.29
0.01 μM 80.94 ± 8.15 16.24 ± 6.77 2.8 ± 1.57 93,14 ± 2,06 5,98 ± 1,69 0,85 ± 0,42 95.7 ± 1.44 3.45 ± 1.63 0.83 ± 0.37
0.1 μM 76.84 ± 9.32 20.15 ± 8.06 2.99 ± 1.34 92,47 ± 1,33 6,49 ± 1,08 1,03 ± 0,39 95.11 ± 2.6 3.99 ± 2.56 0.88 ± 0.16
1 μM 78.82 ± 7.41 18.05 ± 6.27 3.16 ± 1.29 93,32 ± 1,98 5,86 ± 1,61 0,8 ± 0,43 93.32 ± 1.51 5.85 ± 1.76 0.8 ± 0.25
10 μM 79.33 ± 7.24 17.75 ± 6.15 2.9 ± 1.19 93,89 ± 1,29 5,4 ± 1,08 0,69 ± 0,28 95.07 ± 1.1 4.17 ± 1.3 0.74 ± 0.2
100 μM 78.1 ± 6.84 18.46 ± 5.92 3.42 ± 1.09 91,65 ± 1,25 7,48 ± 1,14 0,85 ± 0,18 91.82 ± 2.33a 7.26 ± 2.54a 0.9 ± 0.23
  1. Values represent the average ± SEM of three independent experiments. a was considered statistically significant respect to the control (p < 0.05)