Table 1 Percentage of cell cycle phases was measured by flow cytometry after treatment with PINO

Control

1.72 ± 0.3

60.67 ± 4.8

17.01 ± 2.33

20.59 ± 2.46

0.69 ± 0.11

61.57 ± 0.19

16.72 ± 0.86

21.00 ± 0.74

1.23 ± 0.17

56.45 ± 0.2

20.96 ± 1.29

17.91 ± 1.08

0.001 μM

2.57 ± 0.7

60.87 ± 3.37

16.75 ± 1.68

20.23 ± 2.56

0.54 ± 0.03

62.71 ± 0.23

16.70 ± 0.43

20.60 ± 0.73

1.86 ± 0.7

55.32 ± 1.43

22.44 ± 0.34

16.77 ± 1.02

0.01 μM

1.80 ± 0.21

59.16 ± 4.53

17.55 ± 2.68

20.71 ± 2.01

0.62 ± 0.14

61.64 ± 1

16.72 ± 0.25

21.58 ± 0.93

1.67 ± 0.42

54.12 ± 2.3

21.79 ± 0.62

17.36 ± 1.47

0.1 μM

1.32 ± 0.24

59.33 ± 4.15

18.92 ± 1.68

20.35 ± 2.38

0.49 ± 0.02

60.71 ± 0.51

18.41 ± 0.5

20.61 ± 0.64

1.45 ± 0.22

54.84 ± 1.19

20.47 ± 0.53

19.09 ± 1.1

1 μM

1.62 ± 0.29

60.63 ± 4.93

18.56 ± 2.45

19.37 ± 2.48

0.49 ± 0.03

62.99 ± 1.28

16.99 ± 0.62

20.12 ± 1.06

1.85 ± 0.25

54.72 ± 0.65

21.23 ± 0.8

17.58 ± 1.16

10 μM

1.76 ± 0.3

64.85 ± 4.74

17.6 ± 2.38

15.52 ± 2.21

0.57 ± 0.03

61.73 ± 0.65

18.08 ± 0.41

19.62 ± 0.73

1.66 ± 0.12

53.93 ± 1.54

20.23 ± 1.1

19.6 ± 0.84

100 μM

2.29 ± 0.44

73.39 ± 1.69^a

8.34 ± 0.94^a

16.06 ± 1.8

0.81 ± 0.19

63.92 ± 1.13

11.96 ± 0.68^a

23.38 ± 0.85

1.26 ± 0.23

76.1 ± 2.01^a

9.92 ± 1.02^a

9.45 ± 2.1^a