Fig. 5

Cell proliferation. Cell proliferation was measured by CellTiter-Blue® after 24 h of (+)-pinoresinol treatment followed by proliferation periods of 24, 48, 72 and 96 h in MDA-MB-231 (a), MCF7 (b) and MCF10A (c) cells. Data are represented as the mean (±SEM) with respect to the controls, which were set as 100 %, for three independent assays carried out in triplicate. *, † and ∆ denote statistically significant differences relative to the control at p < 0.05 for MDA-MB-231, MCF7 or MCF10A, respectively