Skip to main content
Fig. 10 | BMC Complementary and Alternative Medicine

Fig. 10

From: Paeoniflorin inhibits excitatory amino acid agonist-and high-dose morphine-induced nociceptive behavior in mice via modulation of N-methyl-D-aspartate receptors

Fig. 10

Effects of PF docked in the active sites of NMDA receptor subtypes. a: NR1 gaining −59.53 kcal/mol binding energy, which had one hydrogen bond with Glu406 (2.56 Å) and one with Thr518 (2.51 Å). b: NR2A gaining −128.49 kcal/mol binding energy, which had two hydrogen bonds with Lys484 (1.90 Å and 2.29 Å), one with Ser685 (2.32 Å) and one with Thr686 (2.35 Å). c: NR2B gaining −106.58 kcal/mol binding energy, which had one hydrogen bond with Lys485 (1.96 Å)

Back to article page