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Table 3 Influence of A. podagraria tincture and metformin on plasma values of lipid metabolism in rats receiving dexamethasone; Mean ± S.E.M; Q50 (Q25–Q75), n = 5–6 in each group

From: The influence of goutweed (Aegopodium podagraria L.) tincture and metformin on the carbohydrate and lipid metabolism in dexamethasone-treated rats

  Total cholesterol, mmol/l HDL cholesterol, mmol/l LDL cholesterol, mmol/l VLDL cholesterol, mmol/l Atherogenic index Total lipids, g/l
Intact control 2.38 ± 0.20
2.36
(2.20–2.51)
1.72 ± 0.13
1.64
(1.47–1.93)
0.62 ± 0.05
0.58
(0.57–0.66)
0.20 ± 0.02
0.20
(0.17–0.25)
0.39 ± 0.07
0.44
(0.26–0.50)
2.48 ± 0.18
2.56
(2.10–2.70)
Dexamethasone 2.71 ± 0.30
2.64
(2.20–3.02)
2.03 ± 0.22
2.16
(1.73–2.20)
0.55 ± 0.08
0.59
(0.47–0.59)
0.30 ± 0.04*
0.32
(0.24–0.36)
0.42 ± 0.04
0.42
(0.38–0.45)
2.82 ± 0.23
2.88
(2.61–2.94)
Dexamethasone + metformin, 50 mg/kg 2.62 ± 0.19
2.49
(2.32–2.82)
2.17 ± 0.14
2.20
(1.89–2.29)
0.31 ± 0.10
0.27
(0.23–0.35)
0.30 ± 0.04*
0.28
(0.25–0.34)
0.21 ± 0.06****
0.23
(0.10–0.25)
2.60 ± 0.26
2.54
(2.13–2.77)
Dexamethasone + A. podagraria tincture, 1 ml/kg 2.80 ± 0.15*
2.76
(2.53–2.84)
2.31 ± 0.18**
2.11
(2.07–2.36)
0.24 ± 0.05***,****, *******
0.28
(0.18–0.33)
0.24 ± 0.02
0.26
(0.23–0.28)
0.22 ± 0.03*****,******
0.23
(0.21–0.25)
2.91 ± 0.29
2.79
(2.41–3.16)
Dexamethasone + metformin.
50 mg/kg + A. podagraria tincture, 1 ml/kg
2.92 ± 0.11*
2.87
(2.78–2.92)
2.19 ± 0.06*
2.12
(2.09–2.23)
0.51 ± 0.08
0.43
(0.38–0.66)
0.22 ± 0.03
0.20
(0.16–0.25)
0.33 ± 0.03****
0.33
(0.28–0.38)
2.61 ± 0.17
2.51
(2.35–2.83)
  1. * – p < 0.05 compared to intact control; ** – p < 0.02 compared to intact control; *** – p < 0.01 compared to intact control
  2. **** – p < 0.05 compared to dexamethasone (untreated); ***** – p < 0.01 compared to dexamethasone (untreated)
  3. ****** – p < 0.05 compared to the group receiving metformin and A. podagraria tincture
  4. ******* – p < 0.02 compared to the group receiving metformin and A. podagraria tincture
  5. Medians are highlighted in bold