The influence of goutweed (Aegopodium podagraria L.) tincture and metformin on the carbohydrate and lipid metabolism in dexamethasone-treated rats

Table 2 Influence of A. podagraria tincture and metformin on glucose metabolism in rats receiving dexamethasone; Mean ± S.E.M; Q₅₀ (Q₂₅–Q₇₅), n = 5–7 in each group

Groups	Liver glycogen, mg/g	Glucose level in plasma after anaesthesia, mmol/l	Coefficients of correlation between liver glycogen and plasma glucose
Intact control	13.7 ± 2.72 13.8 (9.44–17.1)	8.13 ± 0.42 8.76 (7.62–8.83)	+0,61 NS
Dexamethasone	39.0 ± 2.76* 37.7** (34.1–40.8)	9.49 ± 0.46 9.03** (8.90–9.37)	−0,37 NS
Dexamethasone + metformin, 50 mg/kg	33.3 ± 5.31* 28.0** (24.4–38.3)	8.98 ± 1.14 8.69 (7.30–10.7)	+0,70 NS
Dexamethasone + A. podagraria tincture, 1 ml/kg	36.0 ± 3.13* 36.0** (34.3–40.2)	8.44 ± 0.49 8.80 (7.60–9.33)	+0,30 NS
Dexamethasone + metformin, 50 mg/kg + A. podagraria tincture, 1 ml/kg	32.7 ± 3.36* 34.0** (29.1–37.8)	8.60 ± 0.31 8.33 (8.13–9.21)	+0,77 NS

** – p < 0.02 compared to intact control; *** – p < 0.01 compared to intact control
Medians are highlighted in bold

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