Table 1 Influence of A. podagraria tincture and metformin on the results of oral glucose tolerance test in rats receiving dexamethasone; Mean ± S.E.M; Q₅₀ (Q₂₅–Q₇₅), n = 5–6 in each group

Intact control

4.38 ± 0.54

4.91

(3.42–5.34)

5.08 ± 0.42

5.34

(4.48–5.83)

6.37 ± 0.77

6.60

(5.60–6.83)

3.91 ± 0.35

3.84

(3.54–4.06)

622 ± 52.8

682

(551–707)

4.93 ± 0.39

5.34

(4.56–5.44)

Dexamethasone

6.01 ± 0.56

5.44

(4.98–6.68)

7.56 ± 0.72^***

6.60

(6.58–7.86)

7.23 ± 0.54

6.60

(6.25–8.15)

6.22 ± 0.43***

5.87

(5.55–6.63)

829 ± 54.9*

785

(720–935)

6.75 ± 0.44**

6.49

(5.83–7.77)

Dexamethasone + metformin, 50 mg/kg

6.27 ± 0.53

6.68

(5.18–7.14)*****

6.33 ± 0.73

6.58

(5.27–7.04)

6.09 ± 0.76

6.25

(5.20–6.70)

4.93 ± 0.33****

4.91

(4.91–5.11)

701 ± 69.1

708

(650–742)

5.83 ± 0.53

5.69

(5.64–6.14)

Dexamethasone + A. podagraria tincture, 1 ml/kg

5.31 ± 0.58

4.78

(4.31–5.81)

8.20 ± 1.46*

6.49

(5.92–9.49)

7.18 ± 1.27

6.00

(5.13–8.25)

6.07 ± 1.05

6.24

(4.79–7.95)

831 ± 136

724

(611–980)

6.69 ± 1.05

5.88

(5.00–7.85)

Dexamethasone + metformin, 50 mg/kg + A. podagraria tincture, 1 ml/kg

4.24 ± 0.62

4.35

(3.26–5.17)

6.68 ± 0.74*

7.53

(6.02–7.68)

5.26 ± 0.72****

6.03

(3.66–6.40)

4.94 ± 0.78

5.11

(4.27–6.29)

649 ± 62.1

638

(576–757)

5.28 ± 0.45****

5.12

(5.11–5.82)