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Table 4 Effects of AF and honey on the Liver and kidney structure

From: Histopathological and biochemical investigations of protective role of honey in rats with experimental aflatoxicosis

Changes/lesions in liver

A (Control) Mean ± SD

B (AF-treated) Mean ± SD

C (AF+Honey-treated) Mean ± SD

P values

1. Enlargement and palaness

-/6b

2/6a

-/6b

*

slight

*

2

*

Moderate

*

*

*

Severe

*

*

*

2. Hydrolic degeneration/ or fatty changes

-/6b

6/6a

6/6c

 

Slight

*

*

4

**

Moderate

*

2

2

Severe

*

4

*

3. Dysplastic hepatocytes

-/bb

6/6a

4/6c

**

Slight

*

*

2

Moderate

*

3

2

Severe

*

3

*

4. Bile-duct proliferation

-/6b

5/6a

2/6c

**

5. Periportal fibrosis

-/6b

6/6a

1/6b

*

Slight

*

2

1

Moderate

*

2

*

Severe

*

2

*

6. Degeneration and necrosis in renal tubule epithelial cells

-/6b

6/6a

2/6c

*

Slight

*

2

2

Moderate

*

4

*

Severe

*

*

*

7. Megalocytosis in renal tubule epithelial cells

-/6b

2/6a

-/6b

 

Slight

*

2

*

 

Moderate

*

*

*

 

Severe

*

*

*

 
  1. The values present the number of rats showing change/number of rats examined in each treatment group. Values with different letters (a, b and c) in same row are significantly different (P <0.01), according to the Chi-Square tests.
  2. *P >0.05
  3. **P <0.01