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Table 3 Effects of AF and honey on antioxidant defense system and MDA contents in various tissues of rats

From: Histopathological and biochemical investigations of protective role of honey in rats with experimental aflatoxicosis

Tissue Parameters A (Control) B (AF-treated) C(AF + Honey-treated)
Mean ± SD Mean ± SD Mean ± SD
Erythrocyte GSH mg/dl 39.5 ± 0.84 38,8 ± 1,2 43,8 ± 1,5
MDA nmol/ml 0,39 ± 0,08 0,69 ± 0,2a 0,49 ± 0,1ab
CAT U/ml 461.1 ± 40.4 112.6 ± 12.1a 401.4 ± 147.1b
GST U/ml 0,62 ± 0,16 0,75 ± 0,39 0,35 ± 0,21
GR U/ml 0.37 ± 0.12 0.7 ± 0.34a 0.85 ± 0.29a
SOD U/ml 428,6 ± 10,5 443,5 ± 3,5 436,5 ± 13,5
Brain GSH mg/g 28.4 ± 4.4 32.5 ± 5.4 33.7 ± 3.8
MDA nmol/g 34.1 ± 2.4 38.1 ± 3.4 38.3 ± 4.7
CAT U/g 54.9 ± 13.3 52.3 ± 21.5 55.6 ± 12.2
GST U/g 2.6 ± 0.3 2.6 ± 0,3 2.8 ± 0,5
GR U/g 0.94 ± 0.2 0.83 ± 0.14 0.73 ± 0.07
SOD U/g 1511.7 ± 115.2 1605.1 ± 55.3 1631.6 ± 55.3
Liver GSH mg/g 27,5 ± 2,1 21,8 ± 0,5a 24,6 ± 1,5
MDA nmol/g 35,4 ± 3,04 73,7 ± 13,8a 49,1 ± 8,1ab
CAT U/g 79,7.4 ± 13.2 30.8 ± 13.7a 66.3 ± 17.6b
GST U/g 8,8 ± 1,2 8,7 ± 2,7 8,5 ± 1,6
GR U/ml 1.34 ± 0.1 0.85 ± 0.11a 0.80 ± 0.19a
SOD U/g 1879,7 ± 36,8 1451,9 ± 275a 1582,5 ± 90a
Kidney GSH mg/g 46.5 ± 0.6 45.7 ± 1.9 45.7 ± 1.8
MDA nmol/g 6.3 ± 2.5 72.9 ± 43.8a 11.9 ± 3.1ab
CAT U/g 24.1 ± 11.9 24.8 ± 14.7 20.7 ± 2.8
GST U/g 6.5 ± 1.1 5.3 ± 0,3 4.6 ± 0,4
GR U/g 0.37 ± 0.1 0.26 ± 0.1 0.3 ± 0.1
SOD U/g 1504.7 ± 161.8 1485.6 ± 303.6 1468.3 ± 250.7
Heart GSH mg/g 36.4 ± 0.9 39.6 ± 2.3 41.1 ± 1.7
MDA nmol/g 7.12 ± 1.2 21.8 ± 1.2a 8.3 ± 3.1b
CAT U/g 22.8 ± 1.5 16.7 ± 4.1 16.7 ± 6.3
GST U/g 2.5 ± 0.19 2.8 ± 0,2 2.17 ± 0,3
GR U/g 1.2 ± 0.16 1.15 ± 0.06 1.15 ± 0.06
SOD U/g 1349.3 ± 69.4 1471.3 ± 78.5 1467.9 ± 8.2
Lungs GSH mg/g 39.9 ± 4.8 27.8 ± 3.5a 39.4 ± 3.2
MDA nmol/g 11.8 ± 2.8 73.4 ± 11.8a 42.3 ± 6.1ab
CAT U/g 43.5 ± 14.2 37.5 ± 17.6 37.5 ± 22.3
GST U/g 6.2 ± 1.3 5.7 ± 1,2 3.3 ± 0,5
GR U/g 1.3 ± 0.14 1.5 ± 0.08 1.2 ± 0.2
SOD U/g 1879.8 ± 36.8 1643.6 ± 112.1a 1582.6 ± 89.9a
  1. Each value represents the Mean ± SD. a: significantly different from control, b: significantly different from B group rats at p < 0.05 (One way ANOVA)