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Fig. 7 | BMC Complementary and Alternative Medicine

Fig. 7

From: Antitumor evaluation of two selected Pakistani plant extracts on human bone and breast cancer cell lines

Fig. 7

Structural cell compartment alterations of MG-63 cells. Laser scanning microscopic analysis of cell compartments (mitochondria, lysosomes, Golgi apparatus, endoplasmic reticulum, and neutral lipids) within MG-63 cells treated with 100 μg/ml BORM or VSM in comparison to the control (DMSO). Cells were counterstained with Hoechst to label the cell nuclei (blue). Notably, exposure to VSM caused a reduced production of lysosomes and a strong increase of neutral lipids. In contrast, BORM treatment revealed an accumulation and augmentation of lysosomes, stronger granularization and formation of Golgi vesicles and a diffuse distribution of neutral lipids

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