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Table 3 Effects of the subchronic oral administration of EOs on organ weights in Swiss mice

From: In vivo toxicity and antitumor activity of essential oils extract from agarwood (Aquilaria crassna)

Organ weight (g) Control EOs 100 mg/kg EOs 500 mg/kg
Male Female Male Female Male Female
Brain 0.40 ± 0.03 0.45 ± 0.07 0.40 ± 0.02 0.46 ± 0.02 0.40 ± 0.03 0.45 ± 0.03
Heart 0.25 ± 0.02 0.19 ± 0.01 0.24 ± 0.03 0.18 ± 0.01 0.24 ± 0.04 0.19 ± 0.01
Liver 2.36 ± 0.55 2.28 ± 0.55 2.22 ± 0.10 2.56 ± 0.19 2.34 ± 0.08 3.10 ± 0.21*
Spleen 0.25 ± 0.02 0.20 ± 0.02 0.20± 0.02 0.21± 0.02 0.20 ± 0.02 0.23 ± 0.02
Kidney 0.29 ± 0.01 0.32 ± 0.01 0.26 ± 0.1 0.25 ± 0.1 0.24 ± 0.03* 0.23 ± 0.07*
Lungs 0.25 ± 0.02 0.23± 0.02 0.24 ± 0.02 0.22 ± 0.02 0.23 ± 0.02 0.24 ± 0.03
Pancreas 0.30±0.05 0.35±0.04 0.29±0.03 0.36±0.02 0.31±0.04 0.36±0.04
  1. Values are presented as mean ± SD, (*P < 0.05)