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Table 2 Effects of the sub chronic oral administration of EOs on hematological parameters in Swiss mice

From: In vivo toxicity and antitumor activity of essential oils extract from agarwood (Aquilaria crassna)

Parameters Control EOs 100 mg/kg EOs 500 mg/kg
Male Female Male Female Male Female
Total protein (g/dL) 6.00 ± 0.89 5.30 ± 1.10 5.67 ± 1.61 5.59± 1.88 6.6 0± 1.38 6.00 ± 1.99
Albumin (g/dL) 3.05 ± 0.68 3.33 ± 0.58 3.00 ± 0.55 4.00 ± 1.18 4.55 ± 058 3.89 ± 0.50
Globulin (g/dL) 3.32 ± 0.22 2.61 ± 0.39 3.00 ± 0.32 3.20 ± 1.94 3.34 ± 0.53 3.98 ± 0.92
Total bilirubin (U/L) <2.00 <2.00 <2.00 <2.00 <2.00 <2.00
Alkaline phosphatase(mmol/l) 143.42 ± 12.74 134.23 ± 3.08 144.73 ± 18.08 131.12 ± 4.50 145.0 ± 20.40 126.9 ± 5.29
Urea (mmol/l) 7.20 ± 0.15 7.19 ± 0.29 6.30 ± 0.2 6.33± 0.22 6.00 ± 0.23 5.19 ± 0.90*
Potassium (mmol/l) 7.50± 0.07 5.92 ± 0.11 6.10 ± 0.04 5.55 ± 0.09 7.50± 0.05 6.36 ± 0.68
Sodium (mmol/l) 149.00 ± 0.12 135.53 ± 0.92 147.50 ± 0.40 139.33 ± 1.10 147.80 ± 0.41 144.33 ± 1.00
Chloride (mmol/l) 116.14 ± 3.29 100.33 ± 0.13 109.00 ± 2.93 100.00 ± 0.50 110.00± 2.10 111.39 ± 1.09
Creatinine (μmol/l) 26.00 ± 1.14 27.11 ± 1.11 27.66± 1.00 27.77 ± 1.10 29.90 ± 1.97 27.00 ± 1.23
Uric acid (μmol/l) 0.17 ± 0.02 0.19.5± 0.06 0.18 ± 0.05 0.20 ±0.05 0.27 ± 0.09* 0.20± 0.09
Total cholesterol(mg/dl) 169.30±9.80 131.33±7.22 122.58±11.10 119.12±5.05 133.00±19.99 99.20±9.90*
Triglyceride (mg/dl) 155.32±6.44 144.50±13.7 132.40 ±7.68 153.30±11.4 129.90±10.50 123.80±7.25
HDL cholesterol (mg/dl) 76.22±6.04 66.80±10.50 68.90±11.30 65.60±11.61 75.52±12.58 71.15± 13.55
  1. Values are presented as mean ± SD, (*P < 0.05)