Table 2 Effects of the sub chronic oral administration of EOs on hematological parameters in Swiss mice
From: In vivo toxicity and antitumor activity of essential oils extract from agarwood (Aquilaria crassna)
Parameters | Control | EOs 100 mg/kg | EOs 500 mg/kg | |||
|---|---|---|---|---|---|---|
Male | Female | Male | Female | Male | Female | |
Total protein (g/dL) | 6.00 ± 0.89 | 5.30 ± 1.10 | 5.67 ± 1.61 | 5.59± 1.88 | 6.6 0± 1.38 | 6.00 ± 1.99 |
Albumin (g/dL) | 3.05 ± 0.68 | 3.33 ± 0.58 | 3.00 ± 0.55 | 4.00 ± 1.18 | 4.55 ± 058 | 3.89 ± 0.50 |
Globulin (g/dL) | 3.32 ± 0.22 | 2.61 ± 0.39 | 3.00 ± 0.32 | 3.20 ± 1.94 | 3.34 ± 0.53 | 3.98 ± 0.92 |
Total bilirubin (U/L) | <2.00 | <2.00 | <2.00 | <2.00 | <2.00 | <2.00 |
Alkaline phosphatase(mmol/l) | 143.42 ± 12.74 | 134.23 ± 3.08 | 144.73 ± 18.08 | 131.12 ± 4.50 | 145.0 ± 20.40 | 126.9 ± 5.29 |
Urea (mmol/l) | 7.20 ± 0.15 | 7.19 ± 0.29 | 6.30 ± 0.2 | 6.33± 0.22 | 6.00 ± 0.23 | 5.19 ± 0.90* |
Potassium (mmol/l) | 7.50± 0.07 | 5.92 ± 0.11 | 6.10 ± 0.04 | 5.55 ± 0.09 | 7.50± 0.05 | 6.36 ± 0.68 |
Sodium (mmol/l) | 149.00 ± 0.12 | 135.53 ± 0.92 | 147.50 ± 0.40 | 139.33 ± 1.10 | 147.80 ± 0.41 | 144.33 ± 1.00 |
Chloride (mmol/l) | 116.14 ± 3.29 | 100.33 ± 0.13 | 109.00 ± 2.93 | 100.00 ± 0.50 | 110.00± 2.10 | 111.39 ± 1.09 |
Creatinine (μmol/l) | 26.00 ± 1.14 | 27.11 ± 1.11 | 27.66± 1.00 | 27.77 ± 1.10 | 29.90 ± 1.97 | 27.00 ± 1.23 |
Uric acid (μmol/l) | 0.17 ± 0.02 | 0.19.5± 0.06 | 0.18 ± 0.05 | 0.20 ±0.05 | 0.27 ± 0.09* | 0.20± 0.09 |
Total cholesterol(mg/dl) | 169.30±9.80 | 131.33±7.22 | 122.58±11.10 | 119.12±5.05 | 133.00±19.99 | 99.20±9.90* |
Triglyceride (mg/dl) | 155.32±6.44 | 144.50±13.7 | 132.40 ±7.68 | 153.30±11.4 | 129.90±10.50 | 123.80±7.25 |
HDL cholesterol (mg/dl) | 76.22±6.04 | 66.80±10.50 | 68.90±11.30 | 65.60±11.61 | 75.52±12.58 | 71.15± 13.55 |