Fig. 4

H3K9ac and H3K27ac and HDAC5 and HATs mRNA expressions in PLE and MPP⁺ treated cells. a 200 μg/ml PLE treatment decreased acetylation levels of H3K9 in 1 mM MPP⁺ treated cells. b PLE treatment did not significantly alter mRNA expressions of HATs in 1 mM MPP⁺ treated cells. c 200 μg/ml PLE treatment increased mRNA expressions of HDAC5 in 1 mM MPP⁺ treated cells. Figure 4 suggested HDAC5 rather than HATs decreases acetylation levels of H3K9. The data was indicated as the mean ± S.E.M. P < 0.05 was defined statistical significance. One-way ANOVA followed by Duncan post hoc test