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Table 1 Effect of tomato and broccoli extract on serum insulin, glucose, on calculated HOMA- IR and R-QUICKI in HFD induced obesity in rats

From: Resistin mediates tomato and broccoli extract effects on glucose homeostasis in high fat diet-induced obesity in rats

Groups Serum insulin (uIU/ml) Serum glucose (mg/dl) HOMA-IR R-QUICKI
Control 2.52 ± 0.28 67.8 ± 3.23 0.43 ± 0.06 0.455 ± 0.01
HFD 44.1 ± 2.14* 169 ± 1.38* 18.5 ± 0.96* 0.25 ± 0.004*
SD 30.9 ± 1.28*,** 156 ± 1.86*,** 11.9 ± 0.41*,** 0.27 ± 0.004*,**
T 200 12.1 ± 0.75*,**,*** 138 ± 3.82*,**,*** 4.15 ± 0.34*,**,*** 0.31 ± 0.008*,**,***
T 400 6.72 ± 0.36*,**,*** 99.3 ± 4.0*,**,*** 1.66 ± 0.15*,**,*** 0.35 ± 0.01*,**,***
B 200 19 ± 0.71*,**,*** 136 ± 3.0*,**,*** 6.39 ± 0.22*,**,*** 0.29 ± 0.004*,**,***
B 400 9.38 ± 0.47*,**,***,**** 115 ± 2.96*,**,***,**** 2.67 ± 0.18*,**,***,**** 0.33 ± 0.008*,**,***,****
CX 9.48 ± 0.53*,**,***,**** 108 ± 2.79*,**,*** 2.54 ± 0.2*,**,***,**** 0.33 ± 0.01*,**,***,****
  1. Tomato and broccoli extracts treatment at different doses significantly reduced serum levels of insulin and glucose in HFD rats. These extracts also significantly reduced HOMA-IR increased R- QUICKI. C = control; HFD = high fat diet; SD = stop diet; T 200 = tomato extract 200 mg/kg; T 400 = tomato 400 mg/kg; B 200 = broccoli 200 mg/kg; B 400 = broccoli 400 mg/kg; CX = Chromax. HOMA-IR = Homeostasis model assessment index for insulin resistance; R-QUICKI = revised quantitative insulin sensitivity check index. Results were expressed as mean ± SEM and analyzed using one-way ANOVA followed by Bonferroni’s post hoc test. *Significant from control at P < 0.0001, **Significant from HFD at P < 0.0001, ***Significant from SD at P < 0.0001, ****Significant from T 400 at P < 0.005. Results were expressed as mean ± SEM and analyzed using one-way ANOVA followed by Bonferroni’s post hoc test