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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Anti-allodynic effect of intrathecal processed Aconitum jaluense is associated with the inhibition of microglial activation and P2X7 receptor expression in spinal cord

Fig. 3

a Changes in P2X7 receptor (P2X7R) expression in the spinal cord ipsilateral to the SNL by Western blot analysis. Bar graphs depicting the relative intensity of P2X7R expression show a gradual increase in P2X7R levels in the ipsilateral dorsal spinal cord. b Effect of intrathecal (i.t.) administration of PA on P2X7R expression in the ipsilateral dorsal spinal cord. Representative blots showing the expression of P2X7R and GAPDH on day 7 following SNL. Intrathecal injection of PA or saline was performed from days 3 to 7. The increase in P2X7R in the ipsilateral dorsal spinal cord was significantly blocked in animals treated with i.t. PA (300 μg). N = 7 per group. *P < 0.05 vs. naive

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