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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Anti-allodynic effect of intrathecal processed Aconitum jaluense is associated with the inhibition of microglial activation and P2X7 receptor expression in spinal cord

Fig. 1

Acute effects of intrathecal (i.t.) processed Aconitum jaluense (PA) on the hind paw withdrawal response to von Frey filaments following spinal nerve ligation (SNL). Time course of paw withdrawal threshold (a) shows an increase in PWT in animals treated with i.t. PA, which peaks within 30 min. The anti-allodynic effect lasted 3 h following i.t. PA. The percentage of maximal possible effect (b) of i.t. PA was 65 % at a dose of 300 μg. N = 8 per each treatment. *P < 0.05, **P < 0.01 vs. saline

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