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Table 1 Effects of acute oral toxicity study after 24 h of administration of Bon-santé cleanser® in mice

From: Safety evaluation of Bon-santé cleanser® polyherbal in male Wistar rats

Treatments

D/TK

Sign of toxicity

Control (Distilled water, 0.1 ml p.o)

0/5

No toxic changes observed

BSC (250 mg/kg, p.o)

0/5

No toxic changes observed

BSC (500 mg/kg, p.o)

0/5

Mild scratching of lower jaw was observed in at least 3 animals in first 2 h

BSC (1000 mg/kg, p.o)

0/5

Slight hyperactive, scratching of lower jaw and weakness in at least 3 animals in first 2 h

BSC (2000 mg/kg, p.o)

0/5

Slight hyperactive, scratching of lower jaw and weakness in at least 3 animals in first 2 h

BSC (4000 mg/kg, p.o)

0/5

Slight hyperactive, scratching of lower jaw and weakness in at least 3 animals in first 2 h

  1. BSCC Bon-santé® cleanser capsule, K D/T Number of mice death/Total number of mice per group (n = 5)