From: Safety evaluation of Bon-santé cleanser® polyherbal in male Wistar rats
Treatments | D/TK | Sign of toxicity |
---|---|---|
Control (Distilled water, 0.1 ml p.o) | 0/5 | No toxic changes observed |
BSC (250 mg/kg, p.o) | 0/5 | No toxic changes observed |
BSC (500 mg/kg, p.o) | 0/5 | Mild scratching of lower jaw was observed in at least 3 animals in first 2 h |
BSC (1000 mg/kg, p.o) | 0/5 | Slight hyperactive, scratching of lower jaw and weakness in at least 3 animals in first 2 h |
BSC (2000 mg/kg, p.o) | 0/5 | Slight hyperactive, scratching of lower jaw and weakness in at least 3 animals in first 2 h |
BSC (4000 mg/kg, p.o) | 0/5 | Slight hyperactive, scratching of lower jaw and weakness in at least 3 animals in first 2 h |