Skip to main content

Advertisement

Table 1 Characteristics of trials included in the meta-analysis

From: Effectiveness and safety of moxibustion for primary insomnia: a systematic review and meta-analysis

a. Moxibustion vs. Western medications
Included trials Eligibility criteria Interventions and treatment duration Sample and characteristics (male female, age, disease duration) Outcome Criteria (effective rate Criteria)
   Trial Control Trial Control
Wu 2014 [59] CD&TETCMD&S Moxibustion
Duration:30d
Estazolam Duration:30d 91;
AGE: 20-75;
Disease duration:3 m-30y
91;
AGE: 20-75;
Disease duration:3 m-30y;
Unclear
Wong 2014 [62] CCMD-3 Moxibustion
Duration:20d
Estazolam
Duration:20d
40 (M: 18, F: 22);
AGE: 18-63 (mean: 38);
Disease duration: 1.5 m-4y
40 (M: 16; F: 24);
AGE: 18-66 (mean: 39);
Disease duration:1.2 m-6y
GCTNPCM
Yu
2012 [60]
-CCMD-3
-ICD10
Moxibustion
Duration:21d
Estazolam
Duration: 14 d
30;
AGE: 13-65;
Disease duration: 1 m-8 y
30;
AGE: 13-65;
Disease duration:1 m-8y;
GCTNPCM
Ju
2009 [54]
Sleep efficiency computation Moxibustion
Duration:10d
Estazolam
Duration: 10 d
40 (M: 18, F: 22);
AGE: 25-75;
Disease duration: 0.5y-5 y
35 (M: 14 F: 21);
AGE: 25-75;
Disease duration:0.5y-5y
Sleep efficiency computation
Yuan 2007 [61] -CCMD-3
-ICD10
Moxibustion
Duration:20d
-Diazepam
-Oryzanol
--VB1
Duration: 20 d
40;
AGE 14-65;
Disease duration: 1 m-10 y;
40;
AGE 14-65;
Disease duration:1 m-10 y;
GCTNPCM
b. Moxibustion vs. oral Chinese medicine
Included trials Eligibility criteria Interventions and treatment duration Sample and characteristics (male female, age, disease duration) Outcome Criteria (effective rate Criteria)
   Trial Control Trial Control
Jiao 2015 [65] -CCMD-3
-CDT&ETCMD&S
-Moxibustion -SanhuangAnshen Decoction Duration: 30d SanhuangAnshen
Decoction
Duration: 30d
80 (M: 37, F: 43);
AGE: (mean: 67.8);
Disease duration: -;
79 (M: -, F: -);
AGE: (mean: 65.1);
Disease duration: -;
CDT&ETCMD&S
Liu 2015 [66] -CCMD-3
-GCTNPCM
Grain-moxibustion
Duration: 14 d
Renshenguipi pill
Duration: 14 d
38;
AGE: 18-70;
Disease duration: -;
38;
AGE: 18-70;
Disease duration: -;
GCTNPCM
Zhang 2014 [68] -CCMD-3 -Moxibustion
-Huatanjieyu decoction
Duration: 10 d
Huatanjieyu decoction
Duration: 7 d
59;
AGE: 34-65;
Disease duration: -;
59;
AGE: 34-65;
Disease duration: -;
Unclear
He 2014 [63] -ICD-10-
-GCTNPCM
-Moxibustion -Tianwangbuxin decoction
Duration: 32 d
Tianwangbuxin decoction
Duration: 28 d
30 (M: 12, F: 18);
AGE:30-60
(mean:45.3 ± 4. 4);
Disease duration: -;
30 (M: 13, F: 17);
AGE:31-60
(mean:46.2 ± 5.1);
Disease duration: -;
GCTNPCM
Wu 2010 [67] -CCMD-3
-CDT&ETCMD&S
-Heat-sensitive Moxibustion –AnshenBunao decoction
Duration: 22 d
AnshenBunao decoction
Duration: 22 d
30 (M: 13, F: 17);
AGE:33-74 (mean:46.8);
Disease duration: 1 w-2.7 y
30 (M: 11, F: 19);
AGE:35-75 (mean:45.7);
Disease duration: 1w-2.5 y
GCTNPCM
Hu
2007 [64]
PSQI Moxibustion
Duration: 30 d
AnshenBunao Ye
Duration: 30 d
30 (M: 12, F: 18);
AGE: 19-65;
Disease duration: 24 d-16 y
30 (M: 14, F: 16);
AGE: 18-67;
Disease duration: 20 d-14 y
PSQI
c. Moxibustion vs. other TCM therapies
Included trials Eligibility criteria Interventions and treatment duration Sample and characteristics (male female, age, disease duration) Outcome Criteria (effective rate criteria)
   Trial Control Trial Control
Xie 2015 [77] CCMD-3 -Moxibustion
-Head-acupoint massage
Duration: 28 d
Head-acupoint massage
Duration: 28 d
30 (M: 17, F: 13);
AGE:
(mean: 43.3 ± 13.8 y);
Disease duration: (mean: 11.5 ± 5.3 m);
30 (M: 14, F: 16);
AGE: (mean: 42.7 ± 12.4 y);
Disease duration: (mean: 10.8 ± 4.7 m);
GCTNPCM
Wang 2014 [76] Unclear -Moxibustion
-Point-application
Duration:15 d
Point-application
Duration:15 d
18 (M: 10, F: 8);
AGE:39-65y (mean:45.2 y);
Disease duration: -
18 (M: 11, F: 7);
AGE:41-69y (mean:48.1 y);
Disease duration: -
Unclear
Xu 2014 [78] CD&TETCMD&S -Heat-sensitive Moxibustion
-Head-needle acupuncture
Duration:24 d
Head-needle acupuncture
Duration:24 d
58 (M: -, F: -);
AGE: 18-70 y;
Disease duration: 12 m-60 m
54 (M: -,F: -);
AGE: 18-70 y;
Disease duration: 12 m-60 m
sleep efficiency by international standard
Shu 2014 [75] GCTNPCM -Moxibustion
-Head-acupoint massage
Duration:15 d
Head-acupoint massage
Duration: 15 d
9 (M: 0, F: 9);
AGE: 30-56;
Disease duration: 2 m-7 m
9 (M: 0, F: 9);
AGE: 30-56;
Disease duration: 2 m-7 m
GCTNPCM
Ma 2014 [73] CCMD-3 -Moxibustion
-Auricular-plaster therapy
Duration:47 d
Auricular-plaster therapy
Duration:47 d
99 (M: 38, F: 61);
AGE: 20-64 y
(mean: 38 ± 13 y);
Disease duration: 0.5 y-20y
(mean: 7.48 ± 4.57 y)
96 (M: 33, F: 63);
AGE: 21-62 y
(mean: 37 ± 12 y);
Disease duration: 0.5 y-20 y (mean: 7.13 ± 4.92 y)
unclear
Li 2014 [70] ICD-10 -Moxibustion
-Acupuncture
Duration:21 d
-Acupuncture
Duration:21 d
35 (M: 12, F: 23);
AGE: 20-60 y
(mean: 45 ± 3. 5 y);
Disease duration: 1 m-18 m
(mean: 5.5 ± 4.2 m)
35 (M: 8, F: 27);
AGE: 25-60 (mean: 48 ± 4. 9 y);
Disease duration: 1 m-18 m
(mean: 5.6 ± 0.4 m)
GCTNPCM
Quan 2012 [74] CCMD-2-R -Moxibustion
-Acupuncture
Duration:43 d
Acupuncture
Duration:43 d
36 (M: 15, F: 21);
AGE: 19-67 y
(mean:38.9 y);
Disease duration: 6 m-9 y (mean: 5.3 y);
36 (M: 17, F: 19);
AGE: 20-68 y
(mean:40.6 y);
Disease duration: 5 m-10 y (mean: 5 y);
GCTNPCM
Ao 2011 [69] CCMD-3 -Moxibustion
-Acupuncture
Duration:32-33 d
Acupuncture
Duration:32-33d
34 (M: 13, F: 21);
AGE: (mean:40.54 ± 11.27);
Disease duration: (mean: 9.7 ± 2.45 m);
33 (M: 14, F: 19);
AGE: (mean:39.67 ± 11.93);
Disease duration: (mean: 8.47 ± 1.69 m);
Sleep efficiency by international standard
Li 2011 [5] CCMD-3 -Moxibustion
-Acupuncture
Duration:28 d
Acupuncture
Duration:28 d
100 (M: 46, F: 54);
AGE:
(mean: 35.58 ± 9.87);
Disease duration: (mean: 21.59 ± 7.87 m);
98 (M: 45, F: 53);
AGE: (mean: 36.67 ± 10.93);
Disease duration:(mean: 22.76 ± 8.39 m);
GCTNPCM
Chen 2010 [71] -CCMD-3
-ICD -10
-Moxibustion
-Auricular-plaster therapy
Duration:22-23 d
Auricular-plaster therapy
Duration:22-23d
37 (M: -,F: -);
AGE:18-72 (mean:48);
Disease duration: 2 m-7y
26 (M: -,F: -);
AGE:18-72 (mean:48);
Disease duration: 2 m-7 y
Unclear
Li 2010 [72] -CCMD-2-R
-CD&TETCMD&S
-Thunder-fire moxibustion
-Acupuncture
Duration:10-30 d
Acupuncture
Duration:10-30d
35 (M: 15, F: 20);
AGE: (mean: 35.6);
Disease duration: (mean: 3.3 y);
35 (M: 16, F: 19);
AGE: (mean: 33.6);
Disease duration: (mean: 3.6 y);
GCTNPCM
  1. Twenty-two trials (n = 1,971) conducted in China were included in this study
  2. CCMD-2-R = Chinese classification and diagnostic criteria for mental disorders second edition-revision; CCDM-3 = Chinese classification and criteria for disorders 3rd edition; CDT&ETCMD&S = Criteria of Diagnosis and Therapeutic Effects for TCM Disease and Syndrome; GCTNPCM = Guideline for Clinical Trials of New Patent Chinese Medicine; ICD-10 = International Classification of Disease, 10th Version; PSQI = Pittsburgh Sleep Quality Index; M = month; Y = year; D = day; W = week