Table 2 Effects of selected fractions and their combinations on hepatocyte viability, ALT leakage and MDA formation

Control

100.000 ± 2.600

27.830 ± 4.720

0.131 ± 0.032

paracetamol

51.520 ± 3.510**

78.660 ± 4.850**

0.517 ± 0.053**

paracetamol + silymarin (130 μg/ml)

95.200 ± 6.950*

55.330 ± 4.360*

0.282 ± 0.033*

paracetamol + EaF10 (130 μg/ml)

96.940 ± 6.350*

56.160 ± 2.510*

0.303 ± 0.045*

paracetamol + KgF25 (100 μg/ml)

96.540 ± 4.260*

55.330 ± 3.320*

0.307 ± 0.033*

paracetamol + (EaF10 130 μg/ml + KgF25 10 μg/ml)

96.850 ± 3.920*

55.500 ± 3.000*

0.290 ± 0.041*

paracetamol + (EaF10 130 μg/ml + KgF25 30 μg/ml)

99.620 ± 4.250*

54.33 ± 1.750*

0.277 ± 0.029*

paracetamol + (EaF10 130 μg/ml + KgF25 50 μg/ml)

101.050 ± 1.880*

45.330 ± 5.000*

0.264 ± 0.037*

paracetamol + (KgF25 100 μg/ml + EaF10 13 μg/ml)

97.360 ± 0.590*

54.660 ± 4.310*

0.299 ± 0.060*

paracetamol + (KgF25 100 μg/ml + EaF10 39 μg/ml)

99.760 ± 0.200*

47.500 ± 3.000*

0.273 ± 0.019*

paracetamol + KgF25 100 μg/ml + EaF10 65 μg/ml)

102.360 ± 2.290*

42.160 ± 2.080*

0.235 ± 0.029*

paracetamol + (KgF25 100 μg/ml + EaF10 130 μg/ml)

105.510 ± 2.400* (0.581)

37.330 ± 2.36* (0.945)

0.179 ± 0.013* (0.995)