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Table 1 Effects of crude alkaloids and standardson formalin-induced paw-licking response in mice

From: Scientific investigation of crude alkaloids from medicinal plants for the management of pain

Treatment/Dose Licking time (Sec) Inhibition (%)
1st Phase 2nd Phase 1st Phase 2nd Phase
Control (2 % Tween 80) 48.83 ± 1.627 72.83 ± 1.287 ---- ----
Wf Cr.A 50 mg 22.35 ± 1.231*** 20.12 ± 1.163*** 54.22 72.37
Av Cr.A 50 mg 28.31 ± 1.347** 31.45 ± 1.342*** 42.14 56.81
Ca Cr.A 50 mg 34.75 ± 1.441* 44.39 ± 1.568* 28.68 39.04
Vn Cr.A 50 mg 33.35 ± 1.604* 38.93 ± 1.195** 31.82 46.54
Ph Cr.A 50 mg 24.85 ± 1.289*** 24.53 ± 1.391*** 49.16 66.31
Bp Cr.A 50 mg 27.80 ± 1.468** 33.79 ± 1.416** 43.09 53.60
Indomethacin (10 mg) 39.83 ± 1.541 18.66 ± 1.542*** 18.43 74.37
Morphine (5 mg) 6.416 ± 1.165*** 2.83 ± 1.260*** 86.86 96.11
  1. All the values are expressed as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001 when compared to control group (one way ANOVA followed by Dunnetts: compare all vs control test)
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