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Table 1 Effects of crude alkaloids and standardson formalin-induced paw-licking response in mice

From: Scientific investigation of crude alkaloids from medicinal plants for the management of pain

Treatment/Dose

Licking time (Sec)

Inhibition (%)

1st Phase

2nd Phase

1st Phase

2nd Phase

Control (2 % Tween 80)

48.83 ± 1.627

72.83 ± 1.287

----

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Wf Cr.A 50 mg

22.35 ± 1.231***

20.12 ± 1.163***

54.22

72.37

Av Cr.A 50 mg

28.31 ± 1.347**

31.45 ± 1.342***

42.14

56.81

Ca Cr.A 50 mg

34.75 ± 1.441*

44.39 ± 1.568*

28.68

39.04

Vn Cr.A 50 mg

33.35 ± 1.604*

38.93 ± 1.195**

31.82

46.54

Ph Cr.A 50 mg

24.85 ± 1.289***

24.53 ± 1.391***

49.16

66.31

Bp Cr.A 50 mg

27.80 ± 1.468**

33.79 ± 1.416**

43.09

53.60

Indomethacin (10 mg)

39.83 ± 1.541

18.66 ± 1.542***

18.43

74.37

Morphine (5 mg)

6.416 ± 1.165***

2.83 ± 1.260***

86.86

96.11

  1. All the values are expressed as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001 when compared to control group (one way ANOVA followed by Dunnetts: compare all vs control test)
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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