TY - JOUR AU - Cheng, Jai-Hong AU - Tsai, Chia-Ling AU - Lien, Yi-Yang AU - Lee, Meng-Shiou AU - Sheu, Shyang-Chwen PY - 2016 DA - 2016/06/07 TI - High molecular weight of polysaccharides from Hericium erinaceus against amyloid beta-induced neurotoxicity JO - BMC Complementary and Alternative Medicine SP - 170 VL - 16 IS - 1 AB - Hericium erinaceus (HE) is a well-known mushroom in traditional Chinese food and medicine. HE extracts from the fruiting body and mycelia not only exhibit immunomodulatory, antimutagenic and antitumor activity but also have neuroprotective properties. Here, we purified HE polysaccharides (HEPS), composed of two high molecular weight polysaccharides (1.7 × 105 Da and 1.1 × 105 Da), and evaluated their protective effects on amyloid beta (Aβ)-induced neurotoxicity in rat pheochromocytoma PC12 cells. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-016-1154-5 DO - 10.1186/s12906-016-1154-5 ID - Cheng2016 ER -