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Table 1 Effects of ZGW on early embryo development in high-glucose medium

From: Zuogui Wan rescues the high-glucose-induced damaging effects on early embryo development

ZGW (%)(v/v)

Zygote (n)

Cleaved (%)

Blastocyst (%)

Cell numbers (n)

Regular medium

93

83.9 ± 1.5a

55.9 ± 1.0a

68.4 ± 2.4a

HG medium

97

72.1 ± 1.3be

41.3 ± 1.7b

57.2 ± 1.6be

HG medium (vehicle)

92

71.0 ± 1.6bc

38.0 ± 1.2c

54.0 ± 2.4c

HG medium(0.01 %)

95

80.1 ± 1.0d

50.5 ± 1.0d

63.2 ± 2.2d

HG medium(0.10 %)

94

73.4 ± 1.7e

44.8 ± 2.2e

60.0 ± 1.9e

HG medium(1.00 %)

92

69.6 ± 1.7c

39.1 ± 1.7bc

55.6 ± 2.6bc

  1. Regular medium: KSOM medium with 0.2 mmol/L glucose
  2. HG medium: high glucose medium (KSOM medium with 15.6 mmol/L glucose)
  3. Vehicle: 0.01 % normal serum
  4. Data are presented as mean ± S.E.M
  5. Values with different superscript letters (a,b,c,d,e) within the same column are statistically significant (P < 0.05)